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Comment: ANOVA like approach of edgeR
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Talip
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I am comparing the expression patterns of different tissue cell lines (CellType) under five distinct media conditions (Status). Since the c…
Comment: Merge Replicates vs Mixed Model
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gabriel.hoffman
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It is almost always better to retain the full observed data, if the statistical software is able to model the repeated measures. This is a…
Comment: makeContrastsDream for Interaction
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gabriel.hoffman
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The simplest way to handle contrasts with an interaction term is to create a new variable. Lets consider a simpler case with variables `Se…
Answer: DESeq2 sizefactors counfounded with biological treatment
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James W. MacDonald
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Your question is off-topic for this site, which is primarily intended to help people with technical issues with Bioconductor packages rathe…
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